Bubble Wrap PLUS – November 2026

Bubble Wrap

Can’t get enough of Bubble Wrap? The Bubble Wrap Plus is a monthly paediatric Journal Club reading list from Professor Jaan Toelen (University Hospitals Leuven) and Dr Anke Raaijmakers (Sydney Children’s Hospital). 

This comprehensive list draws on 34 journals, including major and subspecialty paediatric journals. We suggest this list can help you discover relevant or interesting articles for your local journal club or keep a finger on the pulse of paediatric research.

Here are some of the highlights:

Maternal Autoimmune Diseases During Pregnancy and Offspring Type 1 Diabetes

Both maternal and paternal autoimmune diseases similarly increase the risk of offspring type 1 diabetes (T1D), pointing to shared familial susceptibility. But disease-specific variations suggest that intrauterine factors (= maternal) also contribute to T1D risk.

Evening Phone Use and Sleep Outcomes Among Youth

Longer smartphone use in the evening is associated with later sleep onset, delayed sleep offset, and shorter total sleep time in adolescents, while smartphone use immediately before bed increases total wake after sleep onset (= fragmented sleep).

Reducing Intervention and Length of Stay for Neonates With Transient Tachypnea of the Newborn

Using standardised clinical guidelines and standing orders in the electronic medical system for neonates with transient tachypnea safely reduced NICU length of stay from 90 to 51 hours and significantly decreased (unnecessary) medical interventions like IV fluids and peripheral catheters.

Exclusive and Any Breastfeeding, Infant Formula Feeding, and Childhood Growth

Longer durations of exclusive or partial breastfeeding are associated with a BMI and reduced odds of childhood overweight and obesity, while prolonged infant formula feeding is linked to an increased risk of elevated BMI.

Oxygen vs Air at Birth for Moderate- to Late-Preterm Infants: The AIROPLANE Cluster Randomized Crossover Trial

Performing delivery room resuscitation with 30% oxygen versus 21% (room air) for moderate- to late-preterm infants resulted in no significant difference in the proportion of neonates requiring ongoing respiratory support upon leaving the delivery room.

You will find the list is broken down into four sections:

1.Reviews and opinion articles

Cortisol under pressure: can we improve hydrocortisone stress dosing in illness, surgery and psychological stress in children with adrenal insufficiency?

Petkovic G, et al. Arch Dis Child. 2026 Oct 28:archdischild-2026-331183.

Preventing sudden unexpected postnatal collapse: a narrative review.

Bergman KA, et al. Eur J Pediatr. 2026 Oct 26;185(11):893.

Non-invasive ventilation for general paediatricians.

Sundaram M, et al. Eur J Pediatr. 2026 Oct 26;185(11):891

Vulvar Crohn’s disease in children: Diagnostic challenges and therapeutic implications from a literature review.

Ancona S, et al. J Pediatr Gastroenterol Nutr. 2026 Oct 26.

Two approaches, one goal: rethinking breastfeeding promotion in maternity hospitals.

Davanzo R, et al. Eur J Pediatr. 2026 Oct 24;185(11):885.

Hydrocephalus: Treatment, Current Research, and Challenges.

Shahriari A, et al. Pediatrics. 2026 Oct 23:e2025074744.

Beyond RSV: why the bronchiolitis burden in infants will not simply disappear.

Mariani F, et al. Eur J Pediatr. 2026 Oct 22;185(11):873.

Abdominal Tics in Children and Adolescents: A Phenomenology-First Diagnostic Framework and Differential Diagnosis.

Akaltun İ, et al. J Paediatr Child Health. 2026 Oct 16.

Innate and adaptive immunity pathways linking Mycoplasma pneumoniae to pediatric asthma phenotypes.

Filippatos F, et al. Eur J Pediatr. 2026 Oct 12;185(11):830.

Medical child abuse and factitious disorder imposed on another: two diagnoses, one child-a narrative review for paediatricians.

Mimran A, et al. Eur J Pediatr. 2026 Oct 9;185(11):819.

Vitamin B12 in early childhood: a phenotype-guided approach to deficiency and unexpectedly elevated concentrations.

Bufka J, et al. Eur J Pediatr. 2026 Oct 2;185(11):796.

CART-Cell Therapy in Pediatric Acute Lymphoblastic Leukemia: A Review for General Pediatricians.

Grasso A, et al. Pediatrics. 2026 Oct 1;158(4):e2026076924.

AI at the Bedside: An Argument for a Training Wheels Approach.

MacDuffie KE, et al. Pediatrics. 2026 Oct 1;158(4):e2025074896.

Postural Orthostatic Tachycardia Syndrome (POTS): A Review.

Chung TH, et al. JAMA. 2026 Oct 6;336(13):1149-1164.

Gram-Negative Bacterial Resistance.

Tamma PD. N Engl J Med. 2026 Oct 29;395(17):1728-1743.

Decoding functional cough in pediatrics: differentiating tic, psychogenic, and compulsive phenotypes for targeted intervention.

Fan X, et al. Eur J Pediatr. 2026 Oct 13;185(11):840.

2.Original clinical studies

Moderate-to-late preterm birth, common respiratory pathogens, and severe lower respiratory tract infections across childhood.

Zhang X, et al. Eur J Pediatr. 2026 Oct 28;185(11):899

Persistent and recurrent hematochezia in neonates and infants: The role of endoscopy.

Ronci S, et al. J Pediatr Gastroenterol Nutr. 2026 Oct 26.

Influenza vaccination effectiveness in children with underlying medical conditions: a case-control study.

Toledo D, et al. Eur J Pediatr. 2026 Oct 27;185(11):894.

Early serum electrolyte profiles in pediatric sepsis and their association with mortality.

Tan LJ, et al. Eur J Pediatr. 2026 Oct 26;185(11):892.

Somatic Growth Faltering Precedes Brain Growth Deceleration in Preterm Infants: A Window for Intervention.

Ottolini KM, et al. J Pediatr. 2026 Oct 23:115372.

Maternal Autoimmune Diseases During Pregnancy and Offspring Type 1 Diabetes.

Zhang H, et al. JAMA Pediatr. 2026 Oct 26:e264894.

Maternal Autoimmune Diseases and Offspring Type 1 Diabetes.

Knip M. JAMA Pediatr. 2026 Oct 26.

Emergency Department Diagnosis of Concussion in Very Young Children with Head Injury.

Christian J, et al. J Pediatr. 2026 Oct 22:115378.

Cariprazine in the Treatment of Pediatric Patients With Irritability Associated With Autism Spectrum Disorder: A Randomized Controlled Trial.

Findling RL, et al. J Am Acad Child Adolesc Psychiatry. 2026 Oct 22:S0890-8567(26)02200-8.

Diagnostic Pitfalls in Meconium-Related Ileus: Red Flags for Surgical Pathologies in Extremely Low Birth Weight Infants.

Santo K, et al. J Paediatr Child Health. 2026 Oct;62(10):1981-1986.

Mobile Subthreshold Exercise Program (MSTEP) for Youth With Prolonged Concussion Recovery: A Randomized Clinical Trial.

Chrisman SPD, et al. JAMA Pediatr. 2026 Oct 19:e264927.

Evening Phone Use and Sleep Outcomes Among Youth.

Zhao Y, et al. JAMA Pediatr. 2026 Oct 19:e264902

Caustic ingestion in children: A prospective analysis of poor outcome key predictors useful for clinical management optimization.

Gragnaniello P, et al. J Pediatr Gastroenterol Nutr. 2026 Oct 18.

Problematic Social Media Use and Depressive and Anxiety Symptoms in Adolescents.

Nagata JM, et al. Pediatrics. 2026 Oct 19:e2025075060.

The relationship between gut microbiota-friendly diet and the prevalence and severity of asthma in children.

Tan LJ, et al. J Pediatr Gastroenterol Nutr. 2026 Oct 14.

Development of an anthropometric-based algorithm to estimate feeding tube insertion depth in neonates.

Lauritsen JV, et al. J Pediatr Gastroenterol Nutr. 2026 Oct 14.

Allergic load and symptom severity in children with tic disorders: a cross-sectional study.

Lin D, et al. Eur J Pediatr. 2026 Oct 13;185(11):837.

Optimizing Antibiotic Duration for Pneumonia and Sinusitis in the Pediatric Emergency Department.

Saucedo JA, et al. Pediatrics. 2026 Oct 13:e2026076351.

Estimates of Anxiety Symptoms Among US Adolescents.

Bommersbach TJ, et al. JAMA Pediatr. 2026 Oct 12:e264702.

Targeting Parental Risk Factors for Children’s Anxiety: A Factorial Randomized Trial with Three Intervention Components.

Rienks K, et al. J Am Acad Child Adolesc Psychiatry. 2026 Oct 8:S0890-8567(26)02178-7.

Reducing Intervention and Length of Stay for Neonates With Transient Tachypnea of the Newborn.

Krishna S, et al. Pediatrics. 2026 Oct 8:e2025075231.

Antibiotic Choice for Community-Acquired Pneumonia in Children With Medical Complexity.

Ekambaram M, et al. Pediatrics. 2026 Oct 7:e2026076178.

Accuracy of non-invasive smartphone bilirubin measurements on neonates before and during phototherapy.

Zdraveska N, et al. Eur J Pediatr. 2026 Oct 6;185(11):807.

Barriers to Reducing Subthreshold Phototherapy for Neonatal Jaundice.

Chang PW, et al. Pediatrics. 2026 Oct 6:e2026076029.

Paediatricians’ Support for Adolescent Vaping Cessation in Australia: A National Cross-Sectional Study.

Nimmi N, et al. J Paediatr Child Health. 2026 Oct 3.

Exclusive and Any Breastfeeding, Infant Formula Feeding, and Childhood Growth.

D’Hollander CJ, et al. Pediatrics. 2026 Oct 2:e2026076578.

Eye Findings Following Congenital Cytomegalovirus Newborn Screening.

Leahy KE, et al. Pediatrics. 2026 Oct 1;158(4):e2025075586.

Peripheral Blood Eosinophil Count as a Predictor of Corticosteroid Resistance in Paediatric Asthma: A Prospective Observational Study.

Rao SS, et al. J Paediatr Child Health. 2026 Oct;62(10):2003-2011.

Management of Monosymptomatic Nocturnal Enuresis in Children: A Pilot Randomised Control Trial of Body-Worn Versus Bell-and-Pad Alarm Device.

Peck B, et al..J Paediatr Child Health. 2026 Oct;62(10):2012-2018.

A Pilot Placebo-Controlled Randomized Trial of Repeated High-Dose Intravenous Magnesium Sulphate and High-Dose Nebulized Budesonide for Severe Asthma in the Paediatric Emergency Department.

Alansari K, et al. J Paediatr Child Health. 2026 Oct;62(10):1948-1958.

Effectiveness of Oseltamivir in Hospitalized Children With Laboratory-Confirmed Influenza, 2014-2023.

Rytlewski K, et al. JAMA Pediatr. 2026 Oct 1;180(10):1116-1124.

Neonatal Medical Male Circumcision and Child Autism Diagnosis.

McGrath M, et al. Pediatr. 2026 Oct 1;180(10):1105-1115

Risk and protective factors for birth-related clavicle fracture and brachial plexus birth injury: a national cohort study.

Voss S, et al. Arch Dis Child Fetal Neonatal Ed. 2026 Oct 20;111(6):F561-F566.

GLP-1 Receptor Agonist and Bariatric Surgery Utilization Among Adolescents and Young Adults.

Messiah SE, et al. JAMA Pediatr. 2026 Oct 1;180(10):1149-1152.

The public health challenges of children’s and adolescents’ digital media use: applying the digital determinants of health as an interpretive framework.

Holly L, et al. Lancet. 2026 Oct 24;408(10565):1758-1773.

Oxygen vs Air at Birth for Moderate- to Late-Preterm Infants: The AIROPLANE Cluster Randomized Crossover Trial.

Peart SR, et al. JAMA. 2026 Oct 20;336(15):1319-1328.

Arginine Therapy for Sickle Cell Disease Acute Pain Episodes: The STArT Randomized Clinical Trial.

Morris CR, et al. JAMA. 2026 Oct 13;336(14):1228-1236.

3.Guidelines and best evidence

Respiratory support during neonatal intubation and procedural success: a meta-analysis of randomised controlled trials.

Jani P, et al. Arch Dis Child Fetal Neonatal Ed. 2026 Oct 27:fetalneonatal-2026-331145

Nasal high-frequency oscillatory ventilation as primary respiratory support in preterm infants with respiratory distress syndrome: current evidence and clinical implications.

Hafeez S, et al. Eur J Pediatr. 2026 Oct 24;185(11):882.

Paediatric Helicobacter pylori infection and allergic and inflammatory diseases: a contemporary systematic review with meta-analysis.

Tavares M, et al. Eur J Pediatr. 2026 Oct 19;185(11):860.

Oral Health for Adolescents: Clinical Report.

Fisher-Owens SA, et al. Pediatrics. 2026 Oct 19.

Interventions to Support Parents Whose Babies Cry Excessively: Systematic Review.

Bilgin A, et al. Pediatrics. 2026 Oct 15:e2025075063.

Evaluating social validity in practice: Parents’ experiences of an eating intervention for children with avoidant restrictive food intake disorder.

Carlsson E, et al. J Pediatr Gastroenterol Nutr. 2026 Oct 12.

Development and validation of prediction models for any and severe acute kidney injury in children with sepsis.

Li Y, et al. Pediatr Nephrol. 2026 Oct 8.

Clinical Practice Guideline for the Diagnosis and Treatment of Urinary Tract Infection in Children From 8 Days to 5 Years of Age.

Alverson BK, et al. Pediatrics. 2026 Oct 1;158(4):e2026078565.

Care of the Infant With Congenital Cytomegalovirus Infection: Clinical Report.

Tesini BL, et al. Pediatrics. 2026 Oct 1;158(4):e2026078595.

4.Case reports

Group A Streptococcus in an Unexpected Site: Temporal Pyomyositis in 2 Children.

Alves AC, et al. Pediatr Infect Dis J. 2026 Oct 21.

Terra firma-forme dermatosis: an adolescent with a ‘dirty’ neck.

Kayumova L, et al. Arch Dis Child. 2026 Oct 20:archdischild-2026-331413.

An Adolescent With Neurosyphilis.

Owerko D, et al. Pediatrics. 2026 Oct 14:e2026076004.

Case 28-2026: A 19-Year-Old Woman with Fever, Cervical Lymphadenopathy, and Leukopenia.

Cohen EM, et al. N Engl J Med. 2026 Oct 8;395(14):1427-1436.

Paraneoplastic Autoimmune Multiorgan Syndrome: Diagnostic Lessons for Pediatricians.

Cherqaoui B, et al. Pediatrics. 2026 Oct 20:e2025073912.

If we have missed out on something useful or you think other articles are absolutely worth sharing, please add them in the comments!